Acetyl Glutamine

AKA: Aceglutamide, 2490-97-3, L-Glutamine, N2-Acetyl-L-glutamine, Aceglutamida, Aceglutamidum, NEURAMINA
Synthetic
Skin Conditioner
Clean
OriginDerived from the amino acid glutamine, a naturally occurring compound synthesized for cosmetic use. Produced through chemical acetylation of glutamine using acetic anhydride or similar acetylating agents.
N-acetyl-L-glutamine is an N2-acetylglutamine that has L-configuration. It has a role as a human metabolite. It is a N(2)-acyl-L-glutamine, a N-acetyl-L-amino acid and a N(2)-acetylglutamine. It is a conjugate acid of a N-acetyl-L-glutaminate. It is an enantiomer of a N(2)-acetyl-D-glutamine.
Formula
C7H12N2O4
Mol. Weight
188.18
CAS #
2490-97-3
Form
Liquid
State
Solid
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.01–1%
Rinse-off0.1%
0%50%100%
CIR reported use · 2012-2013 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR