Acetyl Methionine

AKA: N-Acetyl-L-methionine, 65-82-7, N-Acetylmethionine, Acetyl-L-methionine, Methionamine, Thiomedon, Acetylmethionine, L-(N-Acetyl)methionine, L-Methionine
Synthetic
Skin Conditioner
Clean
OriginDerived from the amino acid methionine, a compound synthesized from petrochemical or fermentation-based sources. Produced through acetylation of methionine using acetic anhydride or acetyl chloride in chemical synthesis.
N-acetyl-L-methionine is an L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. It has a role as a nutraceutical. It is a N-acetylmethionine, a N-acetyl-L-amino acid and a L-methionine derivative. It is a conjugate acid of a N-acetyl-L-methionine(1-). It is an enantiomer of a N-acetyl-D-methionine.
Solubility 307000
Formula
C7H13NO3S
Mol. Weight
191.25
CAS #
1115-47-5, 65-82-7
Form
Powder
State
Solid
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.00001%
Rinse-offNot reported
0%50%100%
CIR reported use · 2012 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR