Acetyl Proline

Acetyl Proline molecular structure
molecular structure · PubChem
AKA: N-Acetyl-L-proline, 68-95-1, 1-Acetyl-L-proline, (2S)-1-acetylpyrrolidine-2-carboxylic acid, L-Proline, (S)-1-acetylpyrrolidine-2-carboxylic acid, (s)-n-acetylproline, (S)-(-)-N-acetylproline
Synthetic
Emollient
Skin Conditioner
Amino Acid
Not Clean
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Proline
Solubility >23.6 [ug/mL] (The mean of the results at pH 7.4)
Formula
C7H11NO3
Mol. Weight
157.17
CAS #
68-95-1
Form
Powder
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic acetylated amino acid derivative used in modern skincare formulations. Developed to enhance collagen-related benefits and improve the penetration of amino acid-based skincare products.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR