Acryloyloxypropyl Polysilsesquioxane

AKA: Acrylo POSS Cage Mixture MA 0736, 1204591-17-2
Synthetic
Skin Conditioner
Not Clean
OriginSynthesized from silicone polymers and acrylic compounds through chemical cross-linking reactions. Produced by esterification of polysilsesquioxane with acryloyloxypropyl functional groups.
2-Propenoic acid, 1,1',1',1'',1'',1''',1''',1''''-(pentacyclo[9.5.1.13,9.15,15.17,13]octasiloxane-1,3,5,7,9,11,13,15-octaylocta-3,1-propanediyl) ester
Formula
C48H72O28Si8
Mol. Weight
1321.70
CAS #
1204591-17-2
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Nail Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens nails
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR