Allantoin Biotin

AKA: UREA, MONO((3AS, 4S, 6AR)-HEXAHYDRO-2-OXO-1H-THIENO(3, 4-D)IMIDAZOLE-4-PENTANOATE), MONO((3AS-(3A.ALPHA., 4.BETA., 6A.ALPHA.))-HEXAHYDRO-2-OXO-1H-THIENO(3, ALLANTOIN BIOTIN [INCI], 1H-THIENO(3, 4-D)IMIDAZOLE-4-PENTANOIC ACID, COMPD. WITH (2, 5-DIOXO-4-IMIDAZOLIDINYL)UREA (1:1)
Synthetic
Soothing
Skin Conditioner
Barrier Support
B Vitamin
Wound Healer
Not Clean
OriginAllantoin is derived from urea and glyoxal through chemical synthesis; biotin is a B-vitamin synthesized from precursor compounds. Both components are combined through esterification or conjugation to create the dual-action complex ingredient.
Urea, (2,5-dioxo-4-imidazolydinyl)-, compound with 2H-thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3as-(3aalpha,4b,6aalpha)]-
Formula
C14H22N6O6S
Mol. Weight
402.43
CAS #
4492-73-3
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Anti-Sebum
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Nourishing
Protecting
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR