OriginSynthesized from allantoin and galacturonic acid, both derived from chemical precursors or natural sources like comfrey root. Combined through esterification or condensation reactions to create the final compound for cosmetic formulation.
Urea, (2,5-dioxo-4-imidazolydinyl)-, compound with galacturonic acid
Formula
C10H16N4O10
Mol. Weight
352.26
CAS #
5119-24-4
Form
Liquid
State
Solid
Skin Types
●all-skin-types
Best For
Irritation
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Nourishing
Protecting
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
0%50%100%
Reg. limit 2%
FDA OTC limit: 2% (Skin Protectant). Source: FDA OTC Monograph, 21 CFR 347.10.
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