Allantoin Panthenol

AKA: Alpantha, 565227-55-6, Allantoin panthenol [INCI], BUTANAMIDE, COMPD. WITH (2, 5-DIOXO-4-IMIDAZOLIDINYL)UREA (1:1), Orb1698552
Synthetic
Skin Conditioner
B Vitamin
Wound Healer
Clean
Allantoin DL-Panthenol alcohol
Formula
C13H25N5O7
Mol. Weight
363.37
CAS #
565227-55-6
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Quells irritation
Accelerates skin healing
Smooths skin texture
Traditional Use
Pairs allantoin (from comfrey, traditionally used for wound healing) with panthenol (vitamin B5, synthesized in the 1940s). This modern combination was created to provide enhanced skin hydration and conditioning properties.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR