Aminomethyl Propanediol

AKA: 2-Amino-2-methyl-1, 3-propanediol, 115-69-5, 2-Amino-2-methylpropane-1, 3-diol, AMPD, Aminoglycol, Gentimon, 1, 3-Propanediol, Isobutandiol-2-amine, 1-Di(hydroxymethyl)ethylamine
Plant-Derived Synthetic
Humectant
Solvent
Synthetic
Clean
OriginSynthesized from propylene oxide and ammonia through chemical reaction to form the amino alcohol compound. Produced via catalytic condensation of these starting materials under controlled industrial conditions.
2-amino-2-methylpropane-1,3-diol is an aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.
Formula
C4H11NO2
Mol. Weight
105.14
CAS #
115-69-5
Form
Liquid
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Buffering
Provides scent
Maintains optimal pH
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed4 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
4 studies / 4 not sensitizing (CIR 136 and 502 and 630)
Eye Irritant in Testing
2 studies / 2 irritating / reactions slight to severe (CIR 136)
Mixed Skin Irritation Results
5 studies / 2 irritating / 3 not irritating / reactions slight (CIR 136 and 502)
Concentration Guide
Leave-on0.25–2%
Rinse-off0.5–0.9%
0%50%100%
CIR reported use · 2013 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR