Aminopropyl Dimethicone

Aminopropyl Dimethicone molecular structure
molecular structure · PubChem
AKA: Amino Silicone, Conditioning Silicone
Synthetic
Skin Conditioner
Hair Care
Silicone
Clean
OriginSynthesized from dimethicone (polydimethylsiloxane), a silicone polymer derived from silicon and methyl chloride. Produced through aminopropyl functional group attachment to dimethicone via hydrosilylation or amine coupling reactions.
Silicones and siloxanes, dimethyl, 3-aminopropyl methyl, trimethylsilyl terminated
CAS #
99363-37-8
Form
Liquid
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Hair
Softens and detangles hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed4 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.001–3%
Rinse-off0.3–0.66%
0%50%100%
CIR reported use · 2019 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR