Ammonium Glycolate

AKA: Ammonium hydroxyacetate, 35249-89-9, Acetic acid, Monoammonium salt, Hydroxyacetic acid, Ammoniuum salt, GLICONOL L, Ammonium salt (1:1), HYDROXYACETIC ACID AMMONIUM SALT
Synthetic
Rx Active
Not Clean
OriginProduced from glycolic acid and ammonia through acid-base neutralization reactions. The resulting ammonium salt is synthesized to create a buffered compound suitable for skincare formulations.
Acetic acid, hydroxy-, monoammonium salt
Formula
C2H7NO3
Mol. Weight
93.08
CAS #
35249-89-9
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
Functions
Buffering
Keratolytic
A pharmaceutical-grade active. These are the heavy hitters — often prescription-strength or regulated for potency.
Supports cell turnover
Unclogs pores
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 34)
Skin Irritant in Testing (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 34)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2013 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR