Ammonium Glycolate

AKA: Ammonium hydroxyacetate, 35249-89-9, Acetic acid, Monoammonium salt, Hydroxyacetic acid, Ammoniuum salt, GLICONOL L, Ammonium salt (1:1), HYDROXYACETIC ACID AMMONIUM SALT
Synthetic
Rx Active
Chemical Exfoliant
Not Clean
Acetic acid, hydroxy-, monoammonium salt
Effective at 36.95%
Formula
C2H7NO3
Mol. Weight
93.08
CAS #
35249-89-9
Form
Liquid
State
Liquid
Functions
Buffering
Keratolytic
A pharmaceutical-grade active. These are the heavy hitters — often prescription-strength or regulated for potency.
Supports cell turnover
Unclogs pores
Traditional Use
Developed in the latter 20th century as a salt of glycolic acid, a naturally occurring alpha-hydroxy acid (AHA). Glycolic acid itself was historically derived from sugarcane, but the ammonium salt form is a modern innovation for skincare exfoliation.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
ewg-5
medical-approval
all-shades-safe
Mild Irritant
Concentration Guide
3.89%
70.0%
0%98%
Reported use
CIR reported use: 7.04-14.29b (70% aq; | pH 3.89-4.01)
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR