Ammonium Glycyrrhizate

AKA: AMMONIUM GLYCYRRHIZINATE, 53956-04-0, Monoammonium glycyrrhizinate, Glycamil, Glycyrram, Monoammonium glycyrrhizate, Ammoniated glycyrrhizin, Glycyrrhizic acid, Ammonium salt, Monoammonium salt
Synthetic
Skin Conditioner
Clean
OriginDerived from glycyrrhizin, the primary active compound extracted from licorice root (Glycyrrhiza glabra). Synthesized through ammoniation of glycyrrhizin, converting the compound into its ammonium salt form.
Monoammonium glycyrrhizinate is an organic molecular entity.
Formula
C42H65NO16
Mol. Weight
840.00
CAS #
53956-04-0
Form
Powder
Skin Types
●all-skin-types, gentle
Best For
Irritation
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Brightens uneven skin tone
Evens pigmentation
Quells irritation
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 349)
Not a Skin Irritant
1 study / 1 not irritating (CIR 349)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR