murphyAmmonium Persulfate
AKA: 7727-54-0, Ammonium peroxydisulfate, Diammonium peroxydisulfate, Diammonium peroxydisulphate, Diammonium persulfate, Ammonium persulphate, Persulfate d'ammonium
Synthetic
Not Clean
OriginSynthesized from ammonium sulfate and hydrogen peroxide through oxidation reactions in industrial chemical facilities. Produced by combining ammonium sulfate with peroxide under controlled conditions to form the persulfate compound.
The CIR Expert Panel concluded that Ammonium, Potassium, and Sodium Persulfate are safe as used as oxidizing agents in hair colorants and hair lighteners designed for brief discontinuous use followed by thorough rinsing from the hair and skin. The Panel also concluded that the available data are insufficient for determining the safety of these persulfates in leave-on products and dentifrices.
Solubility Solubility in water: 83.5 g/100 g water at 25 °C
Formula
H8N2O8S2
Mol. Weight
228.21
CAS #
7727-54-0
Form
Powder
State
Ammonium persulfate appears as a white crystalline solid. A strong oxidizing agent. Does not burn readily, but may cause spontaneous ignition of organic materials. Used as a bleaching agent and as a f
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Bleaching
Oxidising
Brightening
Moisturizing
Strengthens Barrier
Lightens skin tone
Chemical oxidation
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
7
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Skin Irritation Results
5 studies / 1 irritating / 1 mixed / 3 not irritating / reactions severe / plus 1 case report (CIR 257 and 727)
Mixed Eye Irritation Results
3 studies / 1 irritating / 1 mixed / 1 not irritating / reactions minimal to slight (CIR 257)
Mixed Sensitization Results
3 studies / 2 sensitizing / 1 not sensitizing / plus 14 case reports (CIR 257 and 727)
Concentration Guide
Leave-onNot reported
Rinse-off5.8–44.1%
0%50%100%
CIR reported use · 2015 survey
Regulatory Agencies
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR