Ascorbyl Tetraisopalmitate

AKA: 183476-82-6, Tetrahexyldecyl ascorbate, Vitamin C tetra-isopalmitate, VC-IP, Oristar THA, Nikkol BV-OSC, BV-OSC, ORISTAR ATIP, NIKKOL VC-IP
Synthetic
Antioxidant
Emollient
Skin Conditioner
Clean
OriginDerived from plant-based vitamin C sources, typically synthesized from ascorbic acid and palmitic acid esters. Produced through esterification of ascorbic acid with isopalmitic acid to create a stabilized, oil-soluble compound.
L-ascorbic acid, tetraisohexadecanoate
Formula
C70H128O10
Mol. Weight
1129.80
CAS #
161436-56-2, 183476-82-6
Form
Liquid
Skin Types
●all-skin-types, gentle
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 734)
Mixed Sensitization Results
2 studies / 1 sensitizing / 1 not sensitizing / plus 2 case reports (CIR 734)
Concentration Guide
Leave-on0.00001–4%
Rinse-off0.0008–0.05%
0%50%100%
CIR reported use · 2016 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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