Benzophenone-12

AKA: Octabenzone, 2-HYDROXY-4-(OCTYLOXY)BENZOPHENONE, Benzophenone 12, Benzon OO, 2-Hydroxy-4-octoxybenzophenone, Sumisorb 130, Rhodialux P, Seikalizer E, Zislizer E
Synthetic
Sunscreen Filter
Clean
OriginBenzophenone-12 is a synthetic aromatic ketone compound belonging to the benzophenone chemical family of UV absorbers. It is synthesized through the condensation reaction of substituted benzene rings with carbonyl intermediates.
2-Hydroxy-4-octyloxybenzophenone
Solubility In water, <0.001 mg/L at 20 °C, pH 6 /OECD Guideline 105 (Water Solubility)/
Formula
C21H26O3
Mol. Weight
326.40
CAS #
1843-05-6
Form
Powder
State
Dry Powder; Liquid; Other Solid; NKRA; Pellets or Large Crystals
Skin Types
●all-skin-types, gentle
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Caution
Functions
Uv Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Shields from UV damage
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 827)
Not an Eye Irritant
2 studies / 2 not irritating (CIR 827)
Sensitizer in Testing
2 studies / 2 sensitizing (CIR 827)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2021
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR