murphyBenzophenone-2
AKA: 4'-Tetrahydroxybenzophenone, 131-55-5, Bis(2, 4-dihydroxyphenyl)methanone, Methanone, Uvinol D-50, Uvinul D-50, 4, 4'-hydroxybenophenone
Synthetic
Sunscreen Filter
Not Clean
OriginBenzophenone-2 is synthesized from benzophenone, a aromatic ketone compound derived from petroleum-based chemicals. It is produced through selective hydroxylation and sulfonation of benzophenone via chemical synthesis.
2,2',4,4'-Tetrahydroxybenzophenone
Solubility In water, 8,821 mg/L at 24.99 °C
Formula
C13H10O5
Mol. Weight
246.21
CAS #
131-55-5
Form
Powder
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Caution
Functions
Uv Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Shields from UV damage
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 827)
Mixed Phototoxicity Results
Both phototoxic and non-phototoxic results in the CIR safety assessment (CIR 827)
Mixed Sensitization Results
1 study / 1 mixed / plus 3 case reports (CIR 827)
Mixed Eye Irritation Results
3 studies / 1 irritating / 2 not irritating / reactions slight to moderate (CIR 827)
Concentration Guide
0%50%100%
Reg. limit 5%
CIR's newest survey reports no concentration of use.
CIR · 2020 survey
EU/SCCS limit: 5% in cosmetic products. Opinion: SCCS/1679/25
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR