Benzophenone-8

AKA: Dioxybenzone, 131-53-3, 2'-DIHYDROXY-4-METHOXYBENZOPHENONE, Dioxybenzon, Spectra-sorb UV 24, Cyasorb UV 24, Advastab 47, (2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone, Methanone, Dioxibenzona
Synthetic
Sunscreen Filter
Not Clean
OriginBenzophenone-8 belongs to the benzophenone chemical family, synthesized from aromatic hydrocarbon precursors through organic chemistry reactions. Produced via multi-step synthesis involving sulfonation and esterification of benzophenone derivatives under controlled conditions.
2,2'-Dihydroxy-4-methoxybenzophenone
Solubility Practically insoluble in water
Formula
C14H12O4
Mol. Weight
244.24
CAS #
131-53-3
Form
Powder
State
2,2'-dihydroxy-4-methoxybenzophenone is a yellow powder. (NTP, 1992)
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Caution
Functions
Uv Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Shields from UV damage
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 827)
Not an Eye Irritant
1 study / 1 not irritating (CIR 827)
Mixed Skin Irritation Results
3 studies / 1 mixed / 2 not irritating (CIR 827)
Mixed Sensitization Results
2 studies / 1 sensitizing / 1 mixed / plus 1 case report (CIR 827)
Concentration Guide
0%50%100%
Reg. limit 3%
CIR's newest survey reports no concentration of use.
CIR · 2020 survey
FDA OTC limit (Sunscreen): 3%. 21 CFR 352.10
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR