murphyBeta-Caryophyllene
molecular structure · PubChem
AKA: (-)-trans-Caryophyllene, 87-44-5, L-Caryophyllene, Trans-beta-caryophyllene, (-)-Caryophyllene, FEMA No. 2252, (1R, 4E, 9S)-4, 11, 11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene
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Synthetic
Fragrance
Skin Conditioner
Not Clean
OriginDerived from clove plants (Syzygium aromaticum) and other aromatic plants in the Myrtaceae family. Synthesized through isomerization or chemical synthesis of pinene and other terpene precursors.
Bicyclo[7.2.0.]undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-; Caryophyllene; [1R,(1R*,4E,9S*)]-4,11,11-Trimethyl-8-methylene-bicyclo[7.2.0]undec-4-ene; 2-Methylene-6,10,10-trimethylbicyclo[7.2.0]undec-5-ene
Solubility less than 1 mg/mL at 70 °F (NTP, 1992)
Formula
C15H24
Mol. Weight
204.35
CAS #
87-44-5
Form
Oil
State
Beta-caryophyllene is a pale yellow oily liquid with an odor midway between odor of cloves and turpentine. (NTP, 1992)
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR