BHT

AKA: 2, 6-Di-tert-butyl-4-methylphenol, 128-37-0, 6-Di-tert-butyl-p-cresol, Butylhydroxytoluene, 6-Di-t-butyl-4-methylphenol, Ionol, Stavox, Impruvol, Dalpac
Synthetic
Antioxidant
Not Clean
OriginBHT is synthesized from para-cresol, a phenolic compound derived from petroleum hydrocarbons or coal tar. It is produced through alkylation and oxidation reactions that attach tert-butyl groups to the cresol molecule.
2,6-Di-tert-butyl-4-methylphenol is also known as butylated hydroxytoluene (BHT) or butylhydroxytoluene, is a lipophilic (fat-soluble) organic compound that is primarily used as an antioxidant food additive (E number E321) as well as an antioxidant additive in cosmetics, pharmaceuticals, jet fuels, rubber, petroleum products, electrical transformer oil, and embalming fluid. It is also found in certain plants, including soft-necked garlic. A recent study has found that phytoplankton, including the green algae, Botryococcus braunii, as well as three different cyanobacteria (Cylindrospermopsis raciborskii, Microcystis aeruginosa and Oscillatoria sp.) are capable of producing this compound.
Solubility less than 1 mg/mL at 68 °F (NTP, 1992)
Formula
C15H24O
Mol. Weight
220.35
CAS #
128-37-0
Form
Powder
State
Butylated hydroxytoluene is a white crystalline solid. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Reviewed by CIR
Pregnancy
Caution
Restricted By
CIR Safety Findings
Not Phototoxic
CIR Panel statement found no phototoxicity in the CIR safety assessment (CIR 279)
Skin Irritant in Testing
3 studies / 3 irritating / reactions slight to moderate (CIR 279)
Mixed Sensitization Results
2 studies / 1 sensitizing / 1 not sensitizing / plus 7 case reports (CIR 279)
Dermal Absorption 0.07–2.3%
2 results from in vitro tests in the CIR safety assessment (CIR 279)
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR