murphyBis-Diglyceryl Polyacyladipate-1
molecular structure · PubChem
AKA: Polyglyceryl Ester
Synthetic
Emollient
Skin Conditioner
Clean
OriginSynthesized from adipic acid and glycerol through esterification reactions to create a polyester compound. Produced via multi-step esterification and polymerization of fatty acid derivatives with polyhydric alcohols.
Hexanedioic acid, 3-(2,3-dihydroxypropyloxy)-2-hydroxypropyl diester, esters from reaction with a mixture of octanoic, decanoic, isooctadecanoic and 12-hydroxyoctadecanoic acids
CAS #
222722-06-7
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Comedogenic
Animal test found no comedogenicity in the CIR safety assessment (CIR 599)
Not a Skin Irritant
1 study / 1 not irritating (CIR 599)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 599)
Concentration Guide
Leave-on0.2–10%
Rinse-off4%
0%50%100%
CIR reported use · report published 2013
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR