Bis-Diglyceryl Polyacyladipate-2

Bis-Diglyceryl Polyacyladipate-2 molecular structure
molecular structure · PubChem
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Plant-Derived Synthetic
Emollient
Skin Conditioner
Clean
OriginDerived from plant-based glycerin and adipic acid through botanical sourcing of precursor materials. Synthesized through esterification of polyglyceryl compounds with polyacid chains to create the final emollient.
Hexanedioic acid, 3-(2,3-dihydroxypropyloxy)-2-hydroxypropyl diester, esters from reaction with a mixture of octanoic, decanoic, isooctadecanoic, octadecanoic and 12-hydroxyoctadecanoic acids
CAS #
82249-33-0
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Comedogenic
Animal test found no comedogenicity in the CIR safety assessment (CIR 599)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 599)
Mixed Skin Irritation Results
6 studies / 1 irritating / 2 mixed / 3 not irritating / reactions weak to moderate (CIR 599)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions mild (CIR 599)
Concentration Guide
Leave-on0.1–36%
Rinse-off0.2–21%
0%50%100%
CIR reported use · report published 2013
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR