Brucine Sulfate

AKA: Brucine sulphate, 4845-99-2, Brucine sulfate anhydrous, Brucine sulphate anhydrous, Strychnidin-10-one, Sulfate (2:1), 10, 11-DIMETHOXYSTRYCHNINE SULFATE
Synthetic
Clean
2,3-Dimethoxystrychnidin-10-one Sulfate (2:1)
Formula
C46H54N4O12S
Mol. Weight
887.00
CAS #
4845-99-2
Form
Powder
State
Off-white powder; [Sigma-Aldrich MSDS]
Functions
Denaturant
Makes Alcohol Undrinkable
Fights Bacteria
Antioxidant Protection
Reduces Inflammation
Traditional Use
A salt form of the plant alkaloid brucine developed for medicinal applications rather than cosmetics. It has no significant traditional cosmetic use history.
EWG
2
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
ewg-2
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Skin Types
all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
No
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR