Butylene Glycol

AKA: 1, 3-BUTANEDIOL, Butane-1, 3-diol, 107-88-0, 3-Butylene glycol, 3-Dihydroxybutane, Beta-Butylene glycol, Methyltrimethylene glycol, 1-Methyl-1, 3-propanediol, 3 Butylene glycol
Synthetic
Humectant
Solvent
Skin Conditioner
Clean
OriginDerived from petroleum-based hydrocarbons or synthesized from bio-based sources like sugarcane through chemical conversion. Produced through catalytic hydrogenation and oxidation of butene or glucose fermentation followed by chemical synthesis.
Butylene glycol (1.3-Butanediol) is a small organic alcohol used as solvent and conditioning agent.
Formula
C4H10O2
Mol. Weight
90.12
CAS #
107-88-0, 6290-03-5
Form
Liquid
State
Liquid
Skin Types
●all-skin-types, gentle
Best For
Acne
Pregnancy & Breastfeeding Safe
Yes
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Conditioning Agent
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 193)
Not Phototoxic
Product formulation test found no phototoxicity in the CIR safety assessment (CIR 193)
Mixed Eye Irritation Results
4 studies / 3 irritating / 1 not irritating / reactions minimal to severe (CIR 193)
Skin Irritant in Testing
4 studies / 4 irritating / reactions minimal to mild (CIR 193)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR