Calcium Disodium EDTA
molecular structure · PubChem
AKA: Edetate calcium disodium, EDTA calcium disodium, Detoxamin, Edetate calcium disodium anhydrous, Calcium disodium ethylenediaminetetraacetate, INS NO.385, Edetate Calcium Disodium (anhydrous)
Synthetic
Chelating Agent
Clean
Calciate(2-), [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',O(N)-,O(N')-]-, disodium
Solubility Powder. Solubility in water: at 20 °C a 0.1M solution can be prepared (pH approx 7). Pratically insoluble in organic solvents /Tetrahydrate/
Formula
C10H12CaN2Na2O8
Mol. Weight
374.27
CAS #
62-33-9
Form
Powder
State
Pellets or Large Crystals; Liquid, Other Solid; Other Solid; Liquid; Dry Powder
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Reduces Inflammation
Fights Bacteria
Wound Healing
Binds metal ions
Traditional Use
EDTA (ethylenediaminetetraacetic acid) was synthesized in 1935 as a chelating agent. Adopted by cosmetics in the mid-20th century to improve product stability by binding metal ions that cause oxidation and discoloration.
EWG
1
CIR
Reviewed by CIR
Pregnancy
Caution
CIR Safety Findings
ewg-1
pregnancy-nursing-safe
all-shades-safe
Regulatory Agencies
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR