Calcium Disodium EDTA

Calcium Disodium EDTA 1
molecular structure · PubChem CID 6093170
AKA: Edetate calcium disodium, EDTA calcium disodium, Detoxamin, Edetate calcium disodium anhydrous, Calcium disodium ethylenediaminetetraacetate, INS NO.385, Edetate Calcium Disodium (anhydrous)
Synthetic
Chelating Agent
Clean
OriginSynthesized from ethylenediaminetetraacetic acid (EDTA) and sodium salts through acid-base neutralization reactions. Produced by combining EDTA with sodium hydroxide and calcium chloride to form the chelating complex.
Calciate(2-), [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',O(N)-,O(N')-]-, disodium
Solubility Powder. Solubility in water: at 20 °C a 0.1M solution can be prepared (pH approx 7). Pratically insoluble in organic solvents /Tetrahydrate/
Formula
C10H12CaN2Na2O8
Mol. Weight
374.27
CAS #
62-33-9
Form
Powder
State
Pellets or Large Crystals; Liquid, Other Solid; Other Solid; Liquid; Dry Powder
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Reduces Inflammation
Fights Bacteria
Wound Healing
Binds metal ions
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Reviewed by CIR
Pregnancy
Caution
CIR Safety Findings
Sensitizer in Testing
1 study / 1 sensitizing (CIR 285)
Concentration Guide
Leave-on0.025%
Rinse-off0.000098–0.00059%
0%50%100%
CIR reported use · 2019 survey
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR