Calcium Gluconate

AKA: 299-28-5, Calcium D-gluconate, D-Gluconic acid, Calcium salt (2:1), Calglucon, Calcicol, Calciofon, Calcipur, Calglucol, Dragocal
Synthetic
Chelating Agent
Synthetic
Clean
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate for intravenous use only. Each mL contains: Calcium gluconate 94 mg; calcium saccharate (tetrahydrate) 4.5 mg; water for injection q.s. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium gluconate. Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate.
Solubility Soluble in water, insoluble in ethanol
Formula
C12H22CaO14
Mol. Weight
430.37
CAS #
299-28-5
State
Odourless, white crystalline granules or powder, stable in air
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Skin Conditioning Miscellaneous
Improves skin feel
Binds metal ions
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
General
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR