murphyCalcium Pantothenate
AKA: 137-08-6, D-Calcium pantothenate, Calcium D-pantothenate, Pantholin, Calpan, Pantothenate calcium, Vitamin B5, Calcium salt, Calpanate, Pantothenate de calcium
Synthetic
Skin Conditioner
Hair Care
Clean
OriginSynthesized from pantothenic acid (vitamin B5) or derived from petrochemical precursors through organic chemistry methods. Produced by esterification or salt formation of pantothenic acid with calcium to create the stable pantothenate compound.
beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1),(R)-
Formula
C18H32CaN2O10
Mol. Weight
476.50
CAS #
137-08-6
Form
Powder
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Hair
Skin Conditioning Miscellaneous
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Improves skin feel
Softens and detangles hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 737)
Not a Sensitizer (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 737)
Not an Eye Irritant
1 study / 1 not irritating (CIR 737)
Concentration Guide
Leave-on0.0000005–0.5%
Rinse-off0.0001–0.2%
0%50%100%
CIR reported use · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR