Calcium Pantothenate

AKA: 137-08-6, D-Calcium pantothenate, Calcium D-pantothenate, Pantholin, Calpan, Pantothenate calcium, Vitamin B5, Calcium salt, Calpanate, Pantothenate de calcium
Synthetic
Skin Conditioner
Hair Care
Clean
beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1),(R)-
Formula
C18H32CaN2O10
Mol. Weight
476.50
CAS #
137-08-6
Form
Powder
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Hair
Skin Conditioning Miscellaneous
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Improves skin feel
Softens and detangles hair
Traditional Use
Pantothenic acid (vitamin B5) was discovered in 1933. The calcium salt form was developed for skincare and cosmetics in the mid-20th century to support skin barrier function and reduce irritation.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Mild Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR