murphyCalcium PCA
AKA: Calcium pidolate, Efical, 31377-05-6, CALCIDONE
Synthetic
Humectant
Skin Conditioner
Not Clean
OriginCalcium PCA is synthesized from pyroglutamic acid (PCA), a naturally occurring amino acid derivative, combined with calcium salts. The compound is produced through chemical synthesis by reacting pyroglutamic acid with calcium compounds to form the salt complex.
L-Proline, 5-Oxo, Calcium Salt (2:1)
Formula
C10H12CaN2O6
Mol. Weight
296.29
CAS #
31377-05-6
Form
Powder
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR