Calcium Pyrophosphate

AKA: 7790-76-3, Dicalcium pyrophosphate, Diphosphoric acid, Calcium salt (1:2), Calcium phosphate (Ca2P2O7), Calcium salt, Pyrophosphoric acid, Calcium pyrophosphate (Ca2P2O7), CHEBI:32598
Synthetic
Clean
OriginDerived from inorganic calcium and phosphate salts through synthetic chemical combination. Produced by reacting calcium compounds with phosphoric acid under controlled conditions.
The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Calcium Pyrophosphate...
Solubility Insoluble in water. Soluble in dilute hydrochloric and nitric acids
Formula
Ca2O7P2
Mol. Weight
254.10
CAS #
7790-76-3
Form
Powder
State
Dry Powder
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Abrasive
Oral Care
Physical Exfoliant
Locks In Moisture
Gently polishes surface
Supports dental health
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 710)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 710)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2015 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR