Calcium Xylenesulfonate

AKA: 28088-63-3, Benzenesulfonic acid, Calcium salt (2:1), Calcium;2, 3-dimethylbenzenesulfonate, JNIZKBDDCOPXDZ-UHFFFAOYSA-L, Calcium bis(2, 3-dimethylbenzene-1-sulfonate)
Synthetic
Cleanser
Not Clean
OriginDerived from xylene (a petroleum-derived aromatic hydrocarbon) and sulfonic acid or sulfuric acid reagents. Synthesized through sulfonation of xylene followed by neutralization with calcium hydroxide or calcium carbonate.
Calcium xylenesulfonate
Formula
C16H18CaO6S2
Mol. Weight
410.50
CAS #
28088-63-3
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hydrotrope
Surfactant Cleansing
Surfactant Hydrotrope
Anti-Inflammatory
Boosts Collagen
Antimicrobial
Lifts away dirt and oil
Improves ingredient solubility
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 496)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 496)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR