murphyCaprylhydroxamic Acid
AKA: OCTANOHYDROXAMIC ACID, N-Hydroxyoctanamide, 7377-03-9, Caprylohydroxamic acid, Octanamide, Octanoylhydroxamic acid
Synthetic
Skin Conditioner
Synthetic
Not Clean
OriginDerived from caprylic acid, a saturated fatty acid found in coconut oil and palm oil. Synthesized through hydroxylation and amidation of caprylic acid with hydroxylamine derivatives.
used as ruminal urease inhibitor; structure; RN given refers to unlabeled parent cpd
Formula
C8H17NO2
Mol. Weight
159.23
CAS #
7377-03-9
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Buffering
Removes Metal Ions
Binds metal ions
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
Mixed Sensitization Results
5 studies / 2 sensitizing / 3 not sensitizing / plus 4 case reports (CIR 783)
Mixed Skin Irritation Results
5 studies / 1 irritating / 1 mixed / 3 not irritating / reactions mild to moderate (CIR 783)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions mild (CIR 783)
Concentration Guide
Leave-on0.075–0.25%
Rinse-off0.12–0.3%
0%50%100%
CIR reported use · report published 2025
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR