murphyCaprylyl Glycol
AKA: 2-OCTYLENE GLYCOL, OCTANE-1
Synthetic
Emollient
Skin Conditioner
Clean
OriginDerived from coconut oil or palm oil through glycerin extraction and processing of fatty acids. Synthesized by esterification of caprylic acid with glycol through chemical catalysis.
Octane-1,2-diol is an octanediol.
Formula
C8H18O2
Mol. Weight
146.23
CAS #
1117-86-8
State
Liquid
Skin Types
●all-skin-types, gentle
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
—
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 576)
Not a Sensitizer
5 studies / 5 not sensitizing (CIR 576)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions severe (CIR 576)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating (CIR 576)
Concentration Guide
Leave-on0.00003–5%
Rinse-off0.0004–2%
0%50%100%
CIR reported use · 2010 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR