murphyCeramide 1
AKA: Ceramide 1 [INCI], Stearoyloxyheptacosanoyl-4-hydroxysphinganine, Stearoyloxyheptacosanoyl-C18-phytosphingosine, 4-Octadecanetriol, 2-stearoyloxyheptacosamide, CERAMIDE 1 (RETIRED)
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
OriginCeramide 1 is synthesized from phytosphingosine, a long-chain amino alcohol derived from plant sources or chemically manufactured. It is produced through N-acylation, where a fatty acid chain is attached to the phytosphingosine backbone.
Ceramide 1 (Retired) is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where n has a value ranging from 10 to 20.The INCI Name, Ceramide 1, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 1 will be retained in the retired monograph, and also published with the new name assignment, Ceramide EOP.
Formula
C63H125NO6
Mol. Weight
992.7
CAS #
100403-19-8
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR