Ceramide 2
molecular structure · PubChem
AKA: CERAMIDE NG, N-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, (2S, 3R)-2-(Octadecanoylamino)octadecane-1
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide 2 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 14 to 28 and n has a value ranging from 10 to 16.The INCI Name, Ceramide 2, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 2 will be retained in the retired monograph, and also published with the new name assignment
Formula
C36H71NO4
Mol. Weight
582.0
CAS #
100403-19-8
Form
Liquid
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Discovered as part of the skin's lipid matrix research in the 1980s-1990s. Ceramide 2 is synthetically manufactured to replicate this abundant natural skin ceramide for barrier function restoration.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR