murphyCeramide 3
AKA: Cellapy A Repair, N-Stearoyl Phytosphingosine, N-(octadecanoyl)-4R-hydroxysphinganine
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
OriginSynthesized from phytosphingosine, a long-chain amino alcohol derived from plant sources or chemically manufactured.
Produced through N-acylation of phytosphingosine with fatty acids of varying chain lengths and saturation levels.
Ceramide 3 (Retired) is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where m has a value ranging from 12 to 28 in which the acyl moiety may be saturated, mono-unsaturated, or di-unsaturated and n has a value ranging from 10 to 20.The INCI Name, Ceramide 3, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 3 will be
Formula
C36H73NO4
Mol. Weight
584.0
CAS #
100403-19-8
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 674)
Concentration Guide
Leave-on0.00000001–0.2%
Rinse-off0.000001–0.013%
0%50%100%
CIR reported use · report published 2020
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR