Ceramide 5
molecular structure · PubChem
AKA: Ceramide 5 [INCI], TIC-006, CERAMIDE 5 (RETIRED), CERAMIDE AS (CERAMIDE 5), CERAMIDE 5 (RETIRED) [INCI]
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide 5 (Retired) is the N-acylated sphingolipid having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 in which the acyl moiety may be saturated or mono-unsatuarated and n has a value ranging from 10 to 16. Ceramide 5 is similar to Ceramide 4, however, the acylating hydroxy acids are generally longer in Ceramide 5 than in Ceramide 4.The INCI Name, Ceramide 5, originally developed in 1997, was designated with a retired status in 2014. Fo
Formula
C42H83NO4
Mol. Weight
666.1
CAS #
100403-19-8
Form
Liquid
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Discovered during research into skin lipid composition in the late 20th century. Manufactured synthetically to replicate the skin's natural ceramide profile and strengthen barrier function.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR