Ceramide AS

AKA: 100403-19-8, N-(1, 3, 4-TRIHYDROXYOCTADECAN-2-YL)OCTADEC-9-ENAMIDE, Ceramide VI (AP), ATGQXSBKTQANOH-UHFFFAOYSA-N, MSK164723, 1, 4-Octadecanetriol, 2-(2-Hydroxy) Stearamide
Synthetic
Skin Conditioner
Hair Care
Ceramide
Clean
Members of the class of neutral glycosphingolipids. They are the basic units of SPHINGOLIPIDS. They are sphingoids attached via their amino groups to a long chain fatty acyl group. They abnormally accumulate in FABRY DISEASE.
Formula
C36H71NO4
Mol. Weight
582.00
CAS #
100403-19-8
Form
Liquid
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Developed in the 1990s as a synthetic ceramide designed to mimic natural skin barrier lipids. Created to restore skin hydration and repair compromised skin barriers, particularly for eczema and sensitive skin conditions.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR