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Ceramide Np
AKA “3, 4-OCTADECANETRIOL”
Skin Conditioning
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Ingredient Facts
Ceramide np
AKA: 3, 4-OCTADECANETRIOL
Skin Conditioning · Hair Conditioning · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Ceramide
Clean
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid). It is widely used as a moisturizer in various cosmetic and personal products. Together with ceramide 1, they synergistically improve the skin barrier function in humans.
Formula
C36H71NO4
Mol. Weight
582.00
CAS #
72968-43-5
Form
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Insufficient information provided to describe traditional or historical use.
EWG
1
CIR
Safe as used
Pregnancy
—
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Ceramide Np
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide NP (N-Acylated Phytosphingosine)
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide Np
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
The Design and Optimization of Ceramide NP-Loaded Liposomes to Restore the Skin Barrier.
Şahin Bektay H, Sağıroğlu AA, Bozali K, Güler EM, Güngör S
Pharmaceutics, 2023
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR