Cetethyl Morpholinium Ethosulfate

AKA: 78-21-7, Quaternium-25, Atlas G 263, Ethyl sulfate, N-Cetyl-N-ethylmorpholinium ethyl sulfate, G 251, G 263, G-263, 4-Ethyl-4-hexadecylmorpholinium ethyl sulfate
Synthetic
Preservative
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Not Clean
4-Ethyl-4-hexadecylmorpholinium ethyl sulphate
Formula
C24H51NO5S
Mol. Weight
465.70
CAS #
78-21-7
Form
Liquid
State
Liquid
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Fights Bacteria
Traditional Use
A modern synthetic conditioning agent developed for hair and skincare products. Designed to provide antistatic and detangling benefits in contemporary cosmetic formulations.
EWG
3
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
ewg-3
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR