Cetyl Dimethicone

AKA: Polysiloxanes, Cetyl Me, Di-Me, Hexadecyl-methoxy-methyl-trimethylsilyloxysilane, C21H48O2Si2, CMUDPAKFOFFESL-UHFFFAOYSA-N, Hexadecyl-methoxy-methyl-trimethylsilyloxy-silane
Synthetic
Emollient
Skin Conditioner
Silicone
Clean
OriginDerived from dimethicone, a siloxane polymer belonging to the silicone chemical family. Synthesized by attaching a cetyl alcohol chain to dimethicone through siloxane bond formation.
Siloxanes and silicones, hexadecyl methyl, dimethyl
Formula
C21H48O2Si2
Mol. Weight
388.80
CAS #
191044-49-2
Form
Liquid
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed4 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.1–11.8%
Rinse-off0.001–6%
0%50%100%
CIR reported use · 2019 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR