Cetyl Dimethicone

Cetyl Dimethicone 1
Cetyl Dimethicone 2
Cetyl Dimethicone 3
Cetyl Dimethicone 4
AKA: Polysiloxanes, Cetyl Me, Di-Me, Hexadecyl-methoxy-methyl-trimethylsilyloxysilane, C21H48O2Si2, CMUDPAKFOFFESL-UHFFFAOYSA-N, Hexadecyl-methoxy-methyl-trimethylsilyloxy-silane
Synthetic
Emollient
Skin Conditioner
Silicone
Clean
Siloxanes and silicones, hexadecyl methyl, dimethyl
Formula
C21H48O2Si2
Mol. Weight
388.80
CAS #
191044-49-2
Form
Liquid
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Developed in the mid-20th century as a silicone hybrid combining dimethicone with a cetyl (long-chain alcohol) backbone. Used in cosmetics starting in the 1960s as a skin conditioning and smoothing agent.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-2
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed4 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR