Cetyl Dimethylbutyl Ether

AKA: Cetyl 1, 3-dimethylbutyl ether, ASE 166K, 185143-68-4, 1, 3-Dimethylbutyl hexadecyl ether, Hexadecane, (+-)-CETYL DIMETHYLBUTYL ETHER
Synthetic
Skin Conditioner
Clean
OriginSynthesized from cetyl alcohol and dimethylbutanol, both petroleum-derived or plant-derived alcohol compounds. Produced through ether linkage formation via catalytic condensation of the two alcohol components.
Hexadecane, 1-(1,3-Dimethlbutoxy)-
Formula
C22H46O
Mol. Weight
326.60
CAS #
185143-68-4
Form
Oil
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 831)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 831)
Concentration Guide
Leave-on10–19.3%
Rinse-off13.3%
0%50%100%
CIR reported use · report published 2026
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR