Chlorhexidine

AKA: 55-56-1, Hexadol, Soretol, Fimeil, Sterilon, Tubulicid, Chlorhexidinum, Clorhexidina
Synthetic
Preservative
Not Clean
OriginSynthesized from the chemical family of biguanides, derived from petroleum-based starting materials and organic compounds. Produced through multi-step organic synthesis involving condensation reactions between hexamethylene and chlorinated guanidine compounds.
2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-; Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-
Solubility 800
Formula
C22H30Cl2N10
Mol. Weight
505.40
CAS #
55-56-1
Form
Powder
State
Crystals from methanol; [HSDB]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Oral Care
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Fights Bacteria
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Reviewed by CIR
Pregnancy
Caution
Concentration Guide
0%50%100%
Reg. limit 0.3%
EU regulatory limit: 0.3%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 42.
Regulatory Status
USAunder review
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR