Chlorhexidine Diacetate
molecular structure · PubChem
AKA: Chlorhexidine acetate, 56-95-1, Hibitane diacetate, Chlorohexidine diacetate, 040 Diacetate, Chlorhexidini diacetas
Synthetic
Preservative
Not Clean
N,N'-bis(4-Chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine di(acetate)
Formula
C26H38Cl2N10O4
Mol. Weight
625.50
CAS #
56-95-1
Form
Powder
State
White odorless solid; [Reference #1] White powder; [Aldrich MSDS]
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Oral Care
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Fights Bacteria
Traditional Use
A salt form of chlorhexidine created in the mid-20th century to improve stability and solubility. Used in antimicrobial skincare and personal care products for its enhanced preservative properties.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
ewg-5
medical-approval
all-shades-safe
Concentration Guide
0.3%
0%0%
Reg. Limit
EU regulatory limit: 0.3%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 42.
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR