Citrus hystrix leaf extract

AKA: Makrut Lime, Combave
Plant-Derived
Skin Conditioner
Extract
Clean
Citrus Hystrix Leaf Extract is an extract of the leaves of the Combave, Citrus hystrix, Rutaceae
Family
Rutaceae (Citrus family)
Plant Part
Leaf
Lifeform
Shrub or tree
Climate
Wet tropical
CAS #
91771-50-5
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Citrus hystrix (papeda) is native to Southeast Asia and has been used in traditional Indonesian and Thai medicine for antimicrobial and anti-inflammatory purposes. Leaves were traditionally brewed for medicinal teas and topical remedies.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Antioxidant
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR