Citrus hystrix leaf extract

AKA: Makrut Lime, Combave
Plant-Derived
Skin Conditioner
Extract
Clean
OriginNative to Southeast Asia. Derived from leaves of Citrus hystrix (combava), a Southeast Asian citrus species in the Rutaceae family. Extracted from dried or fresh leaves through solvent extraction or maceration methods.
Citrus Hystrix Leaf Extract is an extract of the leaves of the Combave, Citrus hystrix, Rutaceae
Family
Rutaceae (Citrus family)
Plant Part
Leaf
Lifeform
Shrub or tree
Climate
Wet tropical
CAS #
91771-50-5
Form
Liquid
Skin Types
●all-skin-types
Best For
Antioxidant
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 709)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 709)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2021
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR