Denatonium Benzoate

AKA: 3734-33-6, Bitrex, Lidocaine benzyl benzoate, Aversion, Anispray, Gori, Benzoato de denatonio, Benzoate de denatonium
Synthetic
Clean
OriginSynthesized from benzoic acid and diethylaminoethanol as starting materials within the quaternary ammonium compound family. Produced through esterification and quaternization reactions to create the bitter salt compound.
See also: Denatonium (has active moiety).
Formula
C28H34N2O3
Mol. Weight
446.60
CAS #
3734-33-6
Form
Liquid
State
Solid; [Merck Index] White odorless solid; [EFSA: DAR - Vol. 1]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Allergen Warning
⚠️ EU Fragrance Allergen
Functions
Denaturant
Strengthens Barrier
Provides scent
Makes alcohol undrinkable
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 273)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR