murphyDextran Sulfate
molecular structure · PubChem
AKA: Dextran sodium sulfate
Synthetic
Skin Conditioner
Clean
OriginDerived from dextran, a polysaccharide produced by bacterial fermentation of sucrose. Synthesized through sulfation of dextran using sulfuric anhydride or chlorosulfonic acid reagents.
Sulfuric acid, dextran ester
CAS #
9042-14-2
Form
Powder
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Binding
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 611)
Not a Sensitizer (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 611)
Concentration Guide
Leave-on0.01–0.1%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2016
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR