Dextran Sulfate

Dextran Sulfate molecular structure
molecular structure · PubChem
AKA: Dextran sodium sulfate
Synthetic
Skin Conditioner
Clean
Sulfuric acid, dextran ester
CAS #
9042-14-2
Form
Powder
Functions
Binding
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A sulfated derivative of dextran developed in the mid-20th century for pharmaceutical and cosmetic use as a humectant and skin conditioning agent.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR