Di-t-Butylhydroquinone

AKA: 2, 5-Di-tert-butylhydroquinone, 88-58-4, 5-Di-tert-butylbenzene-1, 4-diol, Dibug, Dybug, Santovar O, 5-Di-tert-butylquinol, Nonflex Alba
Synthetic
Antioxidant
Not Clean
OriginSynthesized from hydroquinone, a benzene derivative, through alkylation with tert-butyl groups. Produced via chemical synthesis involving reaction of hydroquinone with isobutylene under catalytic conditions.
2,5-di-tert-butylbenzene-1,4-diol is a member of the class of hydroquinones that is benzene-1,4-diol substituted by tert-butyl groups at position 2 and 5.
Formula
C14H22O2
Mol. Weight
222.32
CAS #
88-58-4
Form
Powder
State
Off-white crystalline powder; [Alfa Aesar MSDS]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Insufficient data
Pregnancy
Caution
CIR Safety Findings
Skin Irritant in Testing
2 studies / 2 irritating / reactions slight (CIR 10)
Mixed Sensitization Results
3 studies / 1 sensitizing / 2 not sensitizing (CIR 10)
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR