Diazolidinyl Urea

Diazolidinyl Urea molecular structure
molecular structure · PubChem
AKA: 78491-02-8, Diazolidinylurea, Germall 11, Imidazolidinyl urea 11, N'-Bis(hydroxymethyl) urea
Allergen Warning
⚠️ Formaldehyde Releaser
⚠️ Formaldehyde Releaser
Synthetic
Preservative
Not Clean
1-[1,3-bis(Hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
Formula
C8H14N4O7
Mol. Weight
278.22
CAS #
78491-02-8
Form
Liquid
State
Liquid
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Prevents microbial growth
Traditional Use
Synthetic preservative developed in the 1960s-1970s as a formaldehyde-releasing antimicrobial agent. Created to address the need for long-term preservation in cosmetic and personal care products.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
0.5%
0%1%
Reg. Limit
EU regulatory limit: 0.5%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 46.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR