murphyDibutyl Adipate
AKA: 105-99-7, Dibutyl hexanedioate, Di-n-butyl adipate, Hexanedioic acid, Dibutyl ester, Cetiol B, SABODERM DBA
Synthetic
Emollient
Occlusive
Solvent
Skin Conditioner
Clean
OriginSynthesized from adipic acid and butanol through esterification reactions to form a diester compound. Produced via catalytic esterification where adipic acid reacts with butanol under controlled heat and acid catalysts.
Dibutyl adipate is a fatty acid ester.
Solubility Solubility in water, g/100ml at 25 °C: 0.0035 (very poor)
Formula
C14H26O4
Mol. Weight
258.35
CAS #
105-99-7
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Comedogenic
Human test found no comedogenicity in the CIR safety assessment (CIR 409 and 528)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 409)
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 409)
Mixed Eye Irritation Results
4 studies / 2 irritating / 2 not irritating / reactions slight (CIR 9 and 409)
Mixed Skin Irritation Results
13 studies / 6 irritating / 1 mixed / 6 not irritating / reactions slight to moderate (CIR 9 and 409 and 528)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2010 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR