Dibutyl Phthalate

AKA: 84-74-2, Di-n-butyl phthalate, N-Butyl phthalate, Genoplast B, Palatinol C, Celluflex DPB, Unimoll DB, DIBUTYLPHTHALATE
Synthetic
Fragrance
Solvent
Not Clean
OriginDerived from phthalic anhydride and butanol, both petroleum-based chemical compounds. Synthesized through esterification of phthalic anhydride with n-butanol via acid-catalyzed reaction.
Dibutyl phthalate is used in making flexible plastics that are found in a variety of consumer products. It appears to have relatively low acute (short-term) and chronic (long-term) toxicity. No information is available regarding the effects in humans from inhalation or oral exposure to dibutyl phthalate, and only minimal effects have been noted in animals exposed by inhalation. No studies are available on the reproductive, developmental, or carcinogenic effects of dibutyl phthalate in humans. Animal studies have reported developmental and reproductive effects from oral exposure. EPA has classified dibutyl phthalate as a Group D, not classifiable as to human carcinogenicity.
Solubility less than 1 mg/mL at 68 °F (NTP, 1992)
Formula
C16H22O4
Mol. Weight
278.34
CAS #
84-74-2
Form
Liquid
State
N-butyl phthalate is a colorless oily liquid. It is insoluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Sin
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Plasticiser
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Antioxidant
Provides scent
Adds flexibility
Dissolves other ingredients
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
10
CIR
Safe as used · CIR insufficient data requested (2026)
Pregnancy
No
CIR Safety Findings
Not an Eye Irritant
2 studies / 2 not irritating (CIR 200)
Not a Sensitizer
4 studies / 4 not sensitizing (CIR 200)
Not Phototoxic
Product formulation test found no phototoxicity in the CIR safety assessment (CIR 200)
Mixed Skin Irritation Results
7 studies / 2 irritating / 2 mixed / 3 not irritating / reactions slight (CIR 200)
Regulatory Status
USAunder review
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR