Diethanolamine Bisulfate
molecular structure · PubChem
AKA: 59219-56-6, Sulfate (1:1) (salt), Sulfate (1:1), 261-663-1, 2-(2-hydroxyethylamino)ethanol;sulfuric acid, 2'-Iminobis(ethanol) sulphate, Diethanolammonium sulfate
WHAT IS IT?
Synthetic
Not Clean
Bis(2-hydroxyethyl)ammonium hydrogen sulphate
Formula
C4H13NO6S
Mol. Weight
203.22
CAS #
59219-56-6
Form
Powder
WHAT DOES IT DO?
Functions
Buffering
Moisturizing
Antimicrobial
Strengthens Barrier
Maintains optimal pH
Traditional Use
Developed in the 20th century as a synthetic buffering and pH-adjusting agent for cosmetic formulations. Used to stabilize and neutralize acidic ingredients in skincare and haircare products.
IS IT CLEAN?
EWG
4
CIR
Safe as used
Pregnancy
Caution
Restricted By
Credo Beauty
Sephora Clean at Sephora
Target Clean
Whole Foods Premium Body Care
Beauty Heroes
MADE SAFE
EWG VERIFIED
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
✔ permitted
EU
✔ permitted
JAPAN
✔ permitted
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
IS IT FOR ME?
Skin Types
●
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
CAN I TRUST THIS?
The paper trail
🔬
Peer-reviewed
1 paper →
⚖️
Regulatory
0 listings
🛡️
Safety-assessed
1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR