Diethyl Adipate

AKA: 141-28-6, Diethyl hexanedioate, 1, 6-Diethyl hexanedioate, Hexanedioic acid, Diethyl ester, Adipic acid, 6-diethyl ester, Diethylester kyseliny adipove
Synthetic
Emollient
Skin Conditioner
Not Clean
Diethyl adipate is a fatty acid ester.
Solubility Soluble in ethanol and ethyl ether
Formula
C10H18O4
Mol. Weight
202.25
CAS #
141-28-6
Form
Liquid
State
Colorless liquid; [Hawley]
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthetic ester created in the early 20th century for use as a plasticizer and solvent in cosmetics. Designed to improve texture and spreadability of creams and lotions without traditional animal-derived alternatives.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR